21 lines
949 B
Plaintext
21 lines
949 B
Plaintext
ARC -- Assembly by Reduced Complexity
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ARC is a pipeline which facilitates iterative, reference-guided de
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novo assemblies with the intent of:
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- Reducing time in analysis and increasing accuracy of results by only
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considering those reads which should assemble together.
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- Reducing/removing reference bias as compared to mapping-based
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approaches.
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The software is designed to work in situations where a whole-genome
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assembly is not the objective, but rather when the researcher wishes
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to assemble discrete 'targets' contained within next-generation
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shotgun sequence data. ARC decomplexifies the traditionally difficult
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problem of assembly by breaking the reads into small, manageable
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subsets which can then be assembled quickly and efficiently in
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parallel. Applications include those in which the researcher wishes to
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de novo assemble specific content and a set of semi-similar reference
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targets is available to initialize the assembly process.
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