pkgsrc-wip/vsearch/DESCR

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VSEARCH supports de novo and reference based chimera detection,
clustering, full-length and prefix dereplication, rereplication,
reverse complementation, masking, all-vs-all pairwise global
alignment, exact and global alignment searching, shuffling,
subsampling and sorting. It also supports FASTQ file analysis,
filtering, conversion and merging of paired-end reads.
The aim of this project is to create an alternative to the USEARCH
tool developed by Robert C. Edgar (2010).