18 lines
1.1 KiB
Plaintext
18 lines
1.1 KiB
Plaintext
EFMlrs EFMlrs is a Python package combined with a designated workflow that
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makes it easy for users to calculate elementary flux modes (EFMs) using a
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new approach in metabolic modelling - the [mplrs algorithm](http://
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cgm.cs.mcgill.ca/~avis/C/lrs.html). Besides this new approach also [efmtool]
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(https://csb.ethz.ch/tools/software/efmtool.html) is supported, as it uses
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the most common and established algorithm for calculating EFMs - the double
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description method.
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The mplrs algorithm can make use of up to two thousand threads in parallel
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so that for the first time EFMs can be calculated for models that are too
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big to be calculated using tools e.g. efmtool that are based on the double
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description method. Furthermore the EFMlrs package provides a method that
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makes it possible to integrate reaction bounds from the sbml files, so that
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subsets of EFMs can be calculated. This feature is compatible with both
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algorithms, the mplrs algorithm and the efmtool. EFMlrs can be used as a
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stand alone console python program but is flexible enough to be integrated
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in already established workflows
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